Literature Review: Does Testosterone Replacement Therapy Cause Mood Swings?

Angry man yelling and pounding his fist on a table.

Testosterone replacement therapy (TRT) is primarily used to address symptoms of testosterone deficiency, such as fatigue, decreased libido, erectile dysfunction, and depressed mood. This is done by increasing serum testosterone levels to a physiological range (1). The impact of TRT on mood has been extensively studied, with mixed results regarding its potential to cause mood swings. […]

The Impact of Testosterone Replacement Therapy on Mood and Depression

The word Mood written in condensation on a car window

Testosterone Replacement Therapy (TRT) is often discussed in the context of physical health, but its effects on mental well-being are equally significant — for some men even more important. In men with low testosterone levels, TRT can play a vital role in improving mood and alleviating symptoms of depression. Understanding how TRT impacts emotional health […]